With the win over Colorado, Villanova advances to the Elite Eight for the initial time in program history.
Villanova has now defeated Colorado for the second time this season after knocking them off 59-54 earlier in the season.
Villanova is now on a seven-game win streak and has won 14 out of their past 15 games.
Villanova is now 6-6 in NCAA Tournament games.
With the victory, Villanova is just one shy of the most wins in school history set in the 1981-82 season when the program went 29-4.
Villanova is now 7-0 this season on neutral courts.
Villanova has made a three-pointer in 179-straight games.
Colorado held Trish Juhline to a season-low one made field goal.
No Villanova player made more than one field goal in the first half.
The nine-point halftime deficit is the largest halftime deficit the Wildcats have overcome this season.
Courtney Mix notched her fifth double-double of the season.
Villanova set a season-high with 10 blocks. Villanova Records Set in NCAA Mideast Regional or NCAA Tournament
Katie Davis is tied for second-place (5) in a Mideast Regional game for most three-pointers in a game.
Villanova's 17 field goals made is tied for the second lowest in a Mideast Regional game.
Villanova's 10 blocked shots is the second-highest total in a Mideast Regional game.
Colorado Notes
Game marks the initial time Colorado has played a BIG EAST squad in the Sweet 16.
Colorado is now 6-5 all-time against BIG EAST teams.
Colorado is now 3-3 in Sweet 16 play.
Tera Bjorklund has made 134 free throws on the season, which is fifth on Colorado's Individual Season free Throws Made Chart.
Colorado's 12 p.m. EST tip is their earliest of the season. The next earliest was 2 p.m. EST in an 86-43 home win over Detroit Mercy in the second game of the season in Boulder, Colo.
Kate Fagan ends the season just one three-pointer shy (70) of tying the CU Individual season record held by Jenny Roulier and Shelly Sheetz.